BPC-157 vs TB-500
BPC-157
vs
TB-500
The two big recovery peptides — and the most common “which one?” question. Short answer: they do different jobs, which is why they’re so often run together (the “Wolverine” stack).
| BPC-157 | TB-500 | |
|---|---|---|
| Style | Local — often near the injury | Systemic — spreads body-wide |
| Dosing | Daily (short half-life) | Weekly (long half-life) |
| Best-known for | Tendon, ligament & gut repair | Flexibility, scar tissue, whole-body recovery |
| Sport status | Research chemical | WADA-banned |
Carl’s verdict: Not either/or. BPC for the specific injury, TB for systemic recovery — most people who use both report they complement each other. Read BPC-157 · TB-500.
Semaglutide vs Tirzepatide
Semaglutide
vs
Tirzepatide
The two household-name fat-loss peptides — and unlike most of this guide, both are FDA-approved with real human trials.
| Semaglutide | Tirzepatide | |
|---|---|---|
| Receptors | GLP-1 only | GIP and GLP-1 (dual) |
| Avg weight loss (trials) | ~15% | ~20%+ |
| Brand names | Ozempic · Wegovy | Mounjaro · Zepbound |
| Track record | Longer | Newer, stronger numbers |
| Dosing | Weekly, titrated | Weekly, titrated |
Carl’s verdict: On average weight loss, trials favour tirzepatide; semaglutide has the longer history. Both are serious prescription drugs with GI side-effects — titration and supervision matter more than the choice. Read Semaglutide · Tirzepatide.
CJC-1295 vs Ipamorelin vs Sermorelin
The growth-hormone family confuses people because they’re not really rivals — they’re two different jobs.
| Peptide | Type | Role |
|---|---|---|
| CJC-1295 | GHRH analog | Increases the size of the GH pulse |
| Sermorelin | GHRH analog (older) | Same idea, gentler, longer clinical history |
| Ipamorelin | Secretagogue (ghrelin-mimic) | Triggers a clean GH pulse, minimal hunger/cortisol |
Carl’s verdict: GHRH (CJC or Sermorelin) + a secretagogue (Ipamorelin) hit different receptors, so together they produce a bigger pulse than either alone — that’s why CJC-1295 + Ipamorelin is the default pairing. Read CJC-1295 · Ipamorelin · Sermorelin.
Selank vs Semax
Selank
vs
Semax
The Russian nootropic duo. Easiest way to remember them: Selank calms, Semax sharpens.
| Selank | Semax | |
|---|---|---|
| Leans toward | Calm, lower anxiety | Focus, clarity, memory |
| Based on | Tuftsin | ACTH(4-10) |
| Feel | Non-sedating calm | Non-stimulant focus |

No favourites.