Carl read the papersWhat it actually is
Selank is a synthetic analog of tuftsin, an immune-modulating peptide. Russian research explored it as an anti-anxiety agent that also touches focus and immune signalling.
It’s often described as calming without the sedation, tolerance or withdrawal associated with benzodiazepines.
How it’s thought to work
- GABA/serotonin modulation — reported effects on calming neurotransmitter systems.
- BDNF — may influence brain-derived neurotrophic factor.
- Immune signalling — tuftsin heritage gives it immune-modulating activity.
- Non-sedating — calm without the drowsiness of classic anxiolytics.
What the research says
Studied in Russian clinical settings for anxiety; Western independent trials are limited. Nasal-spray delivery is common.
- Anxiety and stress research.
- Focus/attention and mood (reported).
- Studied intranasally and by injection.
Reported protocols
These are the doses the peptide community actually reports running (Reddit & forums), alongside published research — logged for education, not as a recommendation to use.
| Parameter | Commonly reported range |
|---|---|
| Community dose | 250–500 mcg per dose (nasal spray common) |
| Frequency | 1–3× daily, or as-needed for anxiety |
| Route | Intranasal (most popular); subQ |
| Cycle | Short courses (1–3 weeks) |
| Community tip | Nasal is the default; non-sedating; commonly paired with Semax |
Common use cases
| Goal | Community protocol notes |
|---|---|
| Anxiety / calm | 250–500 mcg intranasal as needed |
| Focus support | paired with Semax |
| Short course | 1–3 weeks, non-continuous |
Mixing it (reconstitution)
Freeze-dried peptides must be reconstituted with bacteriostatic water before they can be measured. Carl’s calculator turns “mg in the vial + ml of water + target dose” into “units on the syringe” — and tells you how long the vial lasts.
→ Open the Reconstitution Calculator
Injection & handling
Intranasal spray is the popular route (subQ also works), 250–500 mcg, 1–3×/day as needed for anxiety. Short courses (1–3 weeks). Refrigerate.
Stacks it appears in
- Calm & Sharp — Selank + Semax — the Russian nootropic duo: one calms, one sharpens.
