Carl read the papersWhat it actually is
Liraglutide is a GLP-1 receptor agonist that suppresses appetite and slows gastric emptying.
Its ~13-hour half-life is the key difference from semaglutide — it must be dosed every day, not weekly.
How it’s thought to work
- GLP-1 activation — strong appetite suppression / early satiety.
- Slowed gastric emptying — food sits longer, less hunger.
- Glucose control — improves insulin secretion and blood sugar.
- Short half-life — ~13 h → why it’s a daily injection.
What the research says
FDA/EMA approved — Saxenda for weight, Victoza for type-2 diabetes. The one genuinely approved compound of the newer additions here, with real trials.
- Appetite suppression & weight loss (approved).
- Type-2 diabetes control.
- Daily, not weekly (vs semaglutide).
Reported protocols
These are the doses the peptide community actually reports running (Reddit & forums), alongside published research — logged for education, not as a recommendation to use.
| Parameter | Commonly reported range |
|---|---|
| Community dose | Titrate 0.6→1.2→1.8→2.4→3.0 mg, stepping up ~weekly; 3.0 mg is the top weight dose |
| Frequency | DAILY (not weekly) — same time each day |
| Route | SubQ (rotate abdomen/thigh/arm) |
| Cycle | Continuous / long-term; stopping tends to regain |
| Community tip | Some move the shot to evening to kill nighttime snacking; hold or drop a step if appetite loss is excessive |
Common use cases
| Goal | Community protocol notes |
|---|---|
| Weight loss | titrate to 3.0 mg/day, continuous |
| Type-2 diabetes | Victoza, up to 1.8 mg/day |
| Nighttime snacking | an evening dose is common |
Mixing it (reconstitution)
Freeze-dried peptides must be reconstituted with bacteriostatic water before they can be measured. Carl’s calculator turns “mg in the vial + ml of water + target dose” into “units on the syringe” — and tells you how long the vial lasts.
→ Open the Reconstitution Calculator
Injection & handling
SubQ once daily at the same time (abdomen/thigh/upper arm, rotate). Titrate up ~weekly to limit nausea. It’s a pen/prescription product; store per label (fridge before first use).
Stacks it appears in
- The Reset-style — Liraglutide + BPC-157 — gut support to ease GLP-1 GI side-effects.
